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Was first noted in the 1950s. In 1962, methaqualone was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s for the treatment of insomnia, and as a sedative and muscle relaxant. Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as “ludes” or “sopers” (also “soaps”) in the U.S. and “mandrakes” and “mandies” in the UK, Australia and New Zealand. The substance was sold both as a free base and as salt (hydrochloride). It is also a common date rape drug.
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When it was a legal medicine, methaqualone was available in tablet and capsule form and came in different strengths. Oral Quaaludes dosages was 75-150mg for light sedation. A common prescribed dose was 300mg. Up to 600mg was used for strong sedation. Tolerance develops rapidly and some users may take up to 2000mg daily to achieve the same effects. Onset of action is approximately 30 minutes after taking Quaaludes and duration of action is between 5 to 8 hours.
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